Gorla Lea Plaza Dante-Optic Nerve Hypoplasia-(Argentina)

Name: Gorla Lea Plaza Dante 
Sex: Male
Nationality: Argentinean
Age: 3Y
Diagnosis: Optic Nerve Hypoplasia
Discharge Date: 2018/07/22

Before treatment:
He was born by cesarean and it was found that his eyeballs couldn’t move well when he was 40 days old. He was diagnosed with optic nerve hypoplasia. At present he has light sense, can walk by himself but not well and  he also looks downward.
His spirit is normal, he sleeps and eats well, his defecation and urination functions are normal.

Admission PE:
Bp: 99/70mmHg, Hr: 114/min, breathing rate: 24/min, body temperature: 36.8 degrees. Height 95cm, weight 13Kg. The patient has normal physical development and normal nutrition status. There is no injury or bleeding spots of his skin and mucosa and no blausucht. Chest development was normal, the respiratory sounds in both lungs were clear and there was no dry or moist rales. The heart beat is powerful with regular cardiac rhythm and no obvious murmur in the valves. The abdomen was flat and soft, with no masses or tenderness. The liver and spleen were normal.

Nervous System Examination:
Patient was alert and had normal speech ability. He could not complete the examinations of memory, orientation and calculation ability. Both eyes had a pupil diameter of 3mm, a weak reaction to light and his right eye had a doubtful light chasing ability. He could check the visual field. The eyes fundus examination: the color was orange, normal A/V, the central concave papilla was sparse, the macula development was not good, with an unclear border. The bilateral forehead wrinkle and nasolabial fold are symmetrical, swallowing function and hearing ability were normal, his neck and 4 limbs could move freely. Patient could walk with a wide step basis. His eyes usually look downward and he could not complete the muscle power examination. The 4 limbs muscle tone, tendon reflex and abdomen reflex were normal. The sucking reflex was negative; bilateral palm-jaw reflex were negative. The bilateral Hoffmann sign, Rossilimo sign and Babinski sign of both sides were all negative. He could not complete the sensory system and coordinate movement examination. The meningeal irritation sign was negative.

Treatment:
After the admission, he received 3 nerve regeneration treatments (neural stem cells and mesenchymal stem cells) to repair his damaged nerves, replace dead nerves, nourish nerves, regulate his immune system and improve blood circulation. This was done with rehabilitation training.     

Post-treatment:
After 14 days treatment he was more active and he liked to walk and play much more. His pupils were more sensitive to light reflection and he could perceive the flashlight light source. He now walked better than before.


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