Ceferino Vera-Retinopathy of Prematurity-(Argentina)

Name: Ceferino Vera 
Sex: Male
Nationality: Argentinean
Age: 7Y
Diagnosis: Retinopathy of Prematurity IV(ROP5)

Before treatment:
The patient was born prematurely when his mother was 6 months pregnant, he was put in incubator and had oxygen Inhalation. His family members found he had problems with both eyes so he was taken to hospital and diagnosed with retinopathy. He had no vision, only having light sense. He had laser treatment at 7-9 months to stabilize the position of the retina. At present he is unable to see objects or colors, he only has some light sense.
His spirit is normal. His sleep, diet, urination and defecation abilities are normal.

Admission PE:
Bp: 106/89mmHg, Hr: 90/min, breathing rate: 20/min, body temperature: 36.7 degrees. His height is 130 cm, weight 28Kg. Nutrition status is good with normal physical development. There is no injury or bleeding spots of his skin and mucosa, no blausucht and no yellow stains on the skin. Chest development was normal, the respiratory sounds in both lungs were clear and there was no dry or moist rales. The heart beat is powerful with regular cardiac rhythm and with no obvious murmur in the valves. The abdomen was flat and soft with no masses or tenderness. The liver and spleen were normal.

Nervous System Examination:
Patient was alert and had clear speech. His memory, orientation and calculation abilities were normal . Both pupils were equal in size, round, displayed a clumsy response to light and there was punctiform sediment covering surrounding both the pupils. He could not complete the color or nystagmus examinations, both eyes had light perception ability, he was hollow-eyed. Patient was photaesthesia and preferred to close his eyes. The bilateral forehead wrinkle and nasolabial fold are symmetrical, he could swallow as normal, his hearing ability was normal and his neck can move freely, The 4 limbs muscle tone, muscle power, tendon reflex and abdomen reflex were normal, sucking reflex was negative. Bilateral palm-jaw reflex was negative. The Hoffmann, Rossilimo and Babinski signs of both sides were all negative. His sensory and coordinate movement were basically normal. The meningeal irritation sign was negative.

After the admission he received related examinations and received 4 times cells regenation(neural stem cells and mesenchymal stem cells) treatment to active stem cells, repair his damaged retinal cells, replace dead cells, nourish cells, regulate his immune system and improve blood circulation. This was done along with rehabilitation training.     

After 20 days treatment he did not close his eyes as much, they started to show some bright colour distinguishing ability and he could distinguish cardinal direction of the objects in front of him.

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