Marius-Amyotrophic Lateral Sclerosis-(USA)
Name: Marius
Sex: Male
Nationality: USA
Age: 36Y
Diagnosis: Amyotrophic Lateral Sclerosis
Discharge Date: 2018/01/23
Before treatment:
The patient hurt himself when he played football 2 years ago. One month later his left leg showed muscle atrophy and 2 months after that he was unable to raise the leg. Some days ago he felt pain in his right leg and both his legs became weak. At present he can walk with a walker for a short distance, his balance function is normal. His language ability and swallowing function are both normal.
His spirit is normal but his sleep is bad and he needs medicine to sleep. His urination and defecation functions are normal.
Admission PE:
Bp: 111/74mmHg, Hr: 67/min, breathing rate: 18/min, body temperature: 36.2 degrees. Height: 182.5cm, weight: 80Kg. The patient had small skin damage on his left small toe and left rib area with no other injury or bleeding spots of his skin and mucosa. There was no blausucht, no throat congestion and no tonsil swelling. Chest development is normal and the respiratory sounds in both lungs were normal with no dry or moist rales. The heart beat is strong with regular cardiac rhythm and no obvious murmur in the valves. The abdomen was soft and flat with no masses or tenderness. The liver and spleen were normal, shifting dullness was negative, spinal column is normal and there was no edema in the legs.
Nervous System Examination:
Patient was alert and mental status was good with clear speech. The memory, orientation and calculation abilities were normal. Both pupils were equal in size and round, diameter of 2.5 mm, react well to light and the eyeballs can move freely. Bilateral forehead wrinkle and nasolabial groove were symmetrical, he could close his eyes powerfully, make his tongue extend out normally and his tongue can move freely. He could show teeth as normal. Patient could bulge his cheeks normally and chewing ability was normal. Bilateral soft palate can lift, swallowing function was normal, his neck was soft and he could turn his neck and shrug. There was muscle atrophy of the left leg proximal side, the muscle power of the arms was 5 degrees, hands grip force were normal. Left leg muscle power was 2+ degrees, right leg muscle power was 3- degrees. The muscle tone of the arms and right leg were normal. The left leg was higher than normal. Bilateral biceps reflex and triceps reflex were normal, patellar tendon reflex of both sides were active, the bilateral Achilles tendon reflex could be induced by examination. Bilateral ankle clonus were positive, abdominal reflex were normal. Bilateral palm-jaw reflex were negative, sucking reflex was negative, the Hoffmann sign of both sides could not be induced by examination, the Babinski sign of both sides were a doubtful positive, his sensory examinations were normal by gross measure. The finger opposite movement, fast alternate movement and finger to nose test were normal and the heel-knee-tibia test was normal. The meningeal irritation sign was negative.
Treatment:
After the admission he received 3 nerve regeneration treatments (neural stem cells and mesenchymal stem cells) to repair his damaged nerves, replace dead nerves with new injected stem cells, nourish nerves, regulate his immune system and improve blood circulation. This was done with rehabilitation training.
Post-treatment:
After 14 days treatment his left leg muscle tone reduced, the muscle power of the legs was increased 20% with the right leg muscle power now 4 degrees and the left leg 3 degrees. The left foot toes movement ability got better and he could now walk 20 meters by himself.
