Ryan Nesseth-Amyotrophic Lateral Sclerosis-(USA)

Name: Ryan Nesseth
Sex: Male
Nationality: USA
Age: 46Y
Diagnosis: Amyotrophic Lateral Sclerosis(ALS)

Before treatment:
The patient felt weak in his right hand in July 2017. This was accompanied with fasciculation and muscle atrophy so he went to a local hospital but was not diagnosed. He felt weakness in his limbs 2 months later so went to another hospital in October and in this hospital he was diagnosed with ALS. At present he needs help with dressing, washing and cutting his food to eat. His language ability decreased  by 50%.
His spirit, diet, urination and defecation functions are all normal.

Admission PE:
Bp: 127/83mmHg, Hr: 78/min, breathing rate: 20/min, body temperature: 36.7 degrees. Height: 187cm, weight: 122.5Kg. Blood oxygen concentration was 94%. The patient had normal physical development and the nutrition status was good. There was no injury or bleeding spots of his skin and mucosa, no congestion of throat, chest development was normal with normal movement when he was breathing. The lungs breathing sounds were clear with no rales, the heart beat was powerful with regular cardiac rhythm and no murmurs. The abdomen was soft with no masses or tenderness. His liver and spleen were normal, shifting dullness was negative, spinal column was normal, there was no edema of the legs and the dorsalis pedis pulse was normal.

Nervous System Examination:
Patient was alert, mental status was good. There was a slight slurring in his speech with a soft voice. His memory, calculation and orientation abilities were normal. Both pupils were equal in size, round, diameter of 3 mm, react well to light, with horizontal nystagmus and the eyeballs could move freely. The bilateral forehead wrinkle and nasolabial groove were symmetrical. He could make his tongue extend out as normal and there was  mild tongue muscle atrophy and tremor. Showing the teeth was normal, he could bulge the cheeks powerfully and chewing ability was normal. The bilateral soft palate could lift as normal, pharyngeal reflex was normal and his uvula was in middle. Neck was soft, he could turn his neck or shrug but with less than normal power. He could roll over in bed himself but it was difficult to sit up from a lying position. He could stand and walk. The muscle power of the arms was 3+ degrees, the hand grip force was 4- degrees, the fingers muscle power was 3-4 degrees. The muscle power of the legs was 4 degrees. The 4 limbs muscle tone was normal, tendon reflexes were active, the bilateral Hoffmann sign and Rossilimo sign were negative, the Babinski sign of both sides was positive. Patient could perform the finger to nose test, the fast alternate movement and finger opposite movement but slowly because of weakness. The meningeal irritation sign was negative.

After the admission he received related examinations and received 3 times nerve regeneration(neural stem cells and mesenchymal stem cells) treatment to active stem cells,repair his damaged nerves, replace dead nerves, nourish nerves, regulate his immune system and improve blood circulation. This was done with rehabilitation training.     

After 14 days treatment his liver function improved, his endurance improved, muscle power of the arms increased by 0.5 degrees, his shoulder and fingers could move much more and his leg muscle power improved also. He could now walk with much better gait.

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