Abraham, Samuel, and Lavonia-Facioscapulohumeral Muscular Dystrophy (FSHD)-(Papua New Guinea)

Patient Names: Abraham, Samuel, and Lavonia (Twin brothers and sister)
Twin brother: Samuel，age: 24 years old
Other brother: Abraham, age: 24 years old
Sister: Lavonia, age: 22 years old
Nationality: Papua New Guinea
Diagnosis: Facioscapulohumeral Muscular Dystrophy (FSHD)

Admission Information:
All three siblings presented with progressive muscle weakness in the shoulder girders and limbs, with limitations in their daily activities, including slow and clumsy turning over and getting out of bed. In particular, the youngest sister was unable to turn over on her own. They all showed muscle atrophy in their limbs, with severe atrophy particularly affecting the biceps and triceps in their upper arms. They also showed muscle weakness throughout their limbs, with both arms unable to be raised, and their ankles unable to stand on their own, leading to a slow walking speed and a 'duck walk' gait, with poor motor endurance.

Treatment process:
After a clear diagnosis of "Facioscapulohumeral Muscular Dystrophy (FSHD)" was made, they were provided with CAST therapy and a combination of stem cell therapy using mesenchymal stem cells and neural stem cells, including treatments to repair muscle fibers, nourish muscular tissue, improve circulation, regulate immune function, and performed comprehensive rehabilitation training.

After treatment:
The three siblings have shown improvement in their condition. Their limb muscle volume, especially in the biceps, has significantly increased, doubling in volume. Their lifting strength has significantly increased, with both arms able to lift over their head. Their waist and back strength has increased significantly, as has their ability to rollover and rise from the bed. The youngest sister is able to flip over independently now. All three of them are able to walk independently now. Their standing on toes and duck gait have noticeably improved and their walking speed has significantly increased. They have also been able to extend their walking distance significantly.