Pablo Marcelo Piedrabuena-Epilepsy-(Argentina)

Name: Pablo Marcelo Piedrabuena
Sex: Male
Country: Argentina
Age: 11 years
Diagnosis: 1.Cerebral palsy 2. Secondary Epilepsy 3. Upper Respiratory Tract Infection(cured)
Date of Admission: June 22th, 2015
Treatment Hospital/Period: Wu Medical Center/26 days

Before treatment: 
The patient is a premature baby and was born through cesarean. The patient suffered from frequent epileptic seizure due to oxygen deprivation during birth. He received anti-epileptic therapy in a local hospital. About 15 days later, the patient's disease was under control. But his growth and development was limited. He also suffered from severe delay in movement and cognitive function. From onset of the disease, the patient managed with spasmolysis and tranquilizer medications for a long time. He received rehabilitation in a local rehabilitation school. He came to our center 1 year ago and after the treatment, he became better. His muscle tension was better. He could turn his head and trunk better. He could sit for awhile. His spirit was better and cognitive function was better. He began having interest in things. He didn’t experience epileptic seizure during those days. He took Tizanidina 4mg every night. He couldn’t speak. He had dyscinesia and cognitive disorder. He couldn’t turn over his body or walk. His family wanted a better life for him, so he came to our medical center again and he diagnosed with cerebral palsy.

His spirit was bad, he had difficult to swallow food, so he was fed using fistula. His sleep was good. He had constipation and wore paper diaper. The urine volume and color were normal.

Admission PE:
Bp: 126/80mmHg. Hr: 120/min. Body temperature: 37.0 degree. Weight: 22kgs. Height:125 cm. The thorax had mild extroversion. The respiratory sounds in both lungs were hoarse, there was some gurgling with sputum. There were many sputum and secretions in his throat. The cardiac rhythm of his heart was regular, with no obvious murmur in the valves. Tension in the abdominal muscle. The liver and spleen were normal. Both lower limbs were normal.

Nervous System Examination:
Pablo Marcelo Piedrabuena was alert. He couldn’t speak, he could only phonate. He couldn’t communicate with others. His reaction time was slowly. Both pupils were equal in size and round, both pupils were sensitive to light stimulus. The eye position was abnormal. The eyeballs movement was flexible. There was nystagmus. He couldn’t cooperate with tongue examination. His uvula was in the center of oral. He had difficult to swallow. The muscle of his neck was tense. His head always tilted to the right, he could turn his head to left.  The tension of neck was a little higher. The muscle tension of his four limbs was higher after he was upset, sleeping or quiet. He couldn’t cooperate with muscle power examination. He could sit with other’s help. He could extend his spinal column. When he sat, his lower limbs were pendulous. The abdominal reflex was abnormal, both side tender reflex was over active. The sucking reflex was positive. Both side palm jaw reflex was negative. Bilateral Hoffmann sign and Babinski sign were negative. He couldn’t cooperate with other examination.

Treatment:
After admission, the patient diagnosed as cerebral palsy and secondary epilepsy, he received treatment to initiate his nerve repair and regeneration. He had four times of stem cell injection including neural stem cells and mesenchymal stem cells. He had treatment to activate his endogenous retinal stem cells, improve circulation, nourish nerves and adjust immune system. This was accompanied with rehab training. The patient had upper respiratory tract infection during his stay in our hospital, so he received treatment to diminish inflammation, reduce phlegm and improve his immunity.

Post-treatment:
After treatment, his infection has been controlled. His understanding and reaction were better. He could speak more words. His ability to swallow was better, he could eat some semi-liquid diet. He had more facial communication with his family members. His upper limbs were more flexible than before. His left hand could wave and had slight grip movement. The sound in his throat has reduced. He could control his back and neck muscle better. The muscle tension of four limbs was lower. He has not experienced epilepsy seizure or spasm.