Maria Del Milagro Boscacci Asis-Retinopathy of Prematurity-(Argentina)

Name：Maria Del Milagro Boscacci Asis
Gender：Female
Age：24 years old
Nationality：Argentina
Disease：Retinopathy of Prematurity

Maria Del Milagro Boscacci Asis, female, Argentina, 24 years old, was admitted to the hospital for "Retinopathy of Prematurity" due to "binocular vision loss for 24 years after preterm delivery".

Main symptoms:
Premature delivery at 30 weeks of pregnancy, abnormal retinal development was found 2 months after birth, blindness, light perception, and sensitive to light reflex.

Physical examination:
Blood pressure 123/95mmHg, heart rate 77 beats / min. Normal development and good nutrition. The breath sounds of both lungs were clear, and there were no dry and wet rales. Strong heart sound, regular rhythm, no murmur. The abdomen was flat and soft, and the liver and spleen were not enlarged.

Nervous system physical examination:
The spirit was clear and speaked well. Memory and calculation were normal. The eyes had no sense of light and were slow to reflect light. The forehead pattern was symmetrical and the tongue was in the middle. The muscle strength of the extremities was grade 5. Tendon reflex was normal. The pathological signs were negative. Meningeal irritation sign was negative.

Fundus examination:
Retinal detachment in both eyes. The blood flow in the fundus of both eyes was poor.

The process of diagnosis and treatment:
After admission, completed the relevant examination, clearly diagnosed as "Retinopathy of Prematurity, mild muscle atrophy of both hands", gave mesenchymal stem cells and neural stem cells to start retinal development, nutrition retina and optic nerve, improve circulation, with visual rehabilitation and other treatment.

After treatment:
The patient's condition improved, there was a sense of light, the eyes could locate the light source, the angle of the light source was larger, the outline of the object could be distinguished in front of the eyes, and the shadow of large object could be seen at a distance (3m).
Fundus examination: the fundus is orange, the retina is partially attached, and the blood circulation is improved by 50%.

2025.May.7th 2nd round treatment:
1 year later, Maria Del Milagro returned to Wu Medical Center for a second round of stem cell + CAST treatment. She experienced further repair of her retina, leading to an improvement in her visual function. She can now see a pen at a distance of 30 centimeters in front of her and is able to see her family at 2-3 meters away. She can also distinguish shades of color. Her family is very excited and believes that with the enhancement of stem cell functions and the repair of her retina, she will continue to make further progress in her visual abilities!