Sead Sulejmani Sevdan-Muscular Dystrophy-(Macedonia)-Posted on Jan.19th, 2018

Name: Sead Sulejmani Sevdan
Sex: Male
Nationality: Macedonian
Age: 14Y
Diagnosis: Muscular Dystrophy
Date of Admission: August 4th, 2017
Treatment hospital/period: Wu Medical Center/16 days

Before treatment:
The patient was normal when he was born, he began to walk at the age of 18 months but his walking position was abnormal and it was hard for him to stand up when he fell. At the age of 3 he was unable to climb stairs so he was taken to the hospital and diagnosed with muscular dystrophy. His condition became worse and worse in the next 7 years, his motor functions were bad and he also had muscle atrophy. He was unable to walk 4 years ago, he lost weight and had deformity of the pelvis. At present, he lies on bed, he has deformity of some body parts and he can’t take care of himself at all.
His spirit, sleep and diet are normal. His urination and defecation functions are normal. His height is at the normal range but his weight is lighter than normal.

Admission PE:
Bp: 110/75mmHg, Hr: 86/min, body temperature: 36.7 degrees. weight: 32Kg. He was very thin. There is no injury or bleeding spots of his skin and mucosa, and no yellow stains. Chest was malformed with obvious scoliosis to the right side. The respiratory sounds in both lungs were clear with no dry or moist rales. The heart beat is strong with regular cardiac rhythm and no obvious murmur in the valves. The abdomen was soft and sunken with no masses or tenderness. There was obvious severe muscle atrophy of the shoulder girdles, pelvic girdles, arms and legs. Bilateral knee joints and ankle joints had tendon contracture, his knee joint could not stretch straight, it is around a 145 degree angle. There was mild ankle joints varus, with feet drop, the movement ability was poor.

Nervous System Examination:
Patient was alert and mental status was fine with clear speech. The memory, orientation and calculation abilities were normal. Both pupils were equal in size and round, diameter of 3.5 mm, react well to light and the eyeballs could move freely. Bilateral forehead wrinkle and nasolabial groove are symmetrical. He could close eyes powerfully, show teeth and extend his tongue out as normal. The soft palate could lift as normal. Pharyngeal reflex was normal, neck muscle was weak and he could turn his neck but could not shrug. The muscle power of the arms distal side was 2 degrees,  proximal side was 3 degrees. The hands grip force was 3+ degrees, both legs proximal side muscle power was 1+ degree, distal side was 2- degrees. Muscle tone of all 4 limbs was low. He could roll over in bed himself while he could not sit, stand or walk independently. His 4 limbs tendon reflex and abdominal reflex could not be induced by examination, the bilateral Palm-jaw reflex, Hoffmann sign, Rossilimo sign and Babinski sign were negative. The deep and superficial sensory was normal by gross examination. He could not perform the finger to nose test,  both sides finger opposite movement and fast alternate movement was slow, he could not perform the bilateral Heel-knee-tibia test, the meningeal irritation sign was negative.

Treatment:
After the admission he received related examinations and was diagnosed with MD. He received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair his damaged muscle cells, replace dead cells with new injected stem cells, nourish nerves, regulate his immune system and improve blood circulation. This was done with rehabilitation training.     

Post-treatment:
After 16 days treatment he could take food much better than before, the sleep, urine and stool were regular. His scoliosis alleviated and the muscle power of his trunk improved. Arm muscle power improved. Now his arms distal side was 2+ degrees, proximal side was 3 + degrees, both hands grip force was 4 degrees. Muscle power of the legs proximal side was 2- degrees, distal side was 3- degrees. His knee joints bending was alleviated with the angle now around 170°. His shoulder, back muscles and 4 limbs proximal sides muscle volume all increased.

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