Alan Green-Kennedy’s Disease-(United States)

Patient name: Alan Green
Gender: Male
Age: 43 years old
Nationality: United States
Disease diagnosis: Kennedy’s Disease

Before treatment:
Five years ago, the patient began to show limb weakness, intermittent muscle beating, but the patient did not pay attention to. His limb weakness gradually aggravated, in the past 2 years, there were difficulty in climbing stairs, squatting and standing up, and weakness in mastication. The patient had no sensory disturbance, no inarticulate speech, no difficulty in chewing and swallowing. The examination of electromyography in the local hospital showed neurogenic damage in the anterior horn of the spinal cord. Genetic examination identified as "Kennedy’s Disease".

Admission for physical examination:
The patient's blood pressure 130/80mmHg, pulse 77 beats / min, 20 breaths / min, blood oxygen 97%. His development was normal and his figure was thin. In general, no obvious abnormality was found in the systematic examination of internal medicine.

Nervous system physical examination:
The patient was clear-minded and spoke well. His ability of calculation and orientation was normal. His double pupils were 3mm in diameter, sensitive to light, flexible eye movements and no nystagmus. His forehead lines were symmetrical, his tongue muscles were slightly atrophied and tremor, and his tongue was in the middle. His masticatory muscles were weak. The muscle strength of his shoulder and elbow joints of both upper limbs was grade 4, and the grip strength of both hands was grade 5. The muscle strength of hip joint of both lower limbs was grade 4, the muscle strength of knee joint was grade 4, the muscle strength of ankle foot was 5-grade, and the duck gait showed, muscle atrophy and muscle bundle fibrillation showed at the proximal end of the limbs. The muscle tone of his limbs was normal. The tendon reflex of his extremities was significantly weakened. His deep and shallow senses were normal. The pathological signs were negative. Meningeal irritation sign was negative.

Treatment process:
The patient’s admission diagnosis was "Kennedy’s Disease". During hospitalization, patient was treated with CAST and neural stem cells plus mesenchymal stem cells to repair motor neuropathy, nourish nerve, improve internal environment, immunomodulation and rehabilitation training as a comprehensive treatment.

After treatment:
The patient's condition improved, the motor function of the limbs improved, the muscle strength of both upper limbs increased by 30%, the range of motion of the shoulder joint was significantly expanded, the muscle strength of the shoulder muscle and upper arm was significantly improved, and the lifting force of the upper arm was significantly enhanced. The muscle strength of both lower limbs was 4 +, the leg lifting strength was significantly improved, the walking ability was significantly improved, and the gait was improved. His energy, physical fitness and sports endurance were significantly improved.