Yang SoonRae-Amyotrophic Lateral Sclerosis-(Korea)-Posted on Nov.1st, 2017

Name: Yang SoonRae
Sex: Female
Nationality: Korean
Age: 65Y
Diagnosis: 1. Amyotrophic Lateral Sclerosis(ALS) 2. Diabetes (type 2)
Date of Admission: April 25th, 2017
Treatment hospital/period: Wu Medical Center/14days

Before treatment:
In the summer of 2012, the patient fell some times, she didn’t know the reasons and didn’t care, one year later, she fell more, and she couldn’t move lower limbs well, so she went to hospital in May 2015, the doctor diagnosed her with ALS. One year ago, her felt weakness in upper limbs, especially in right upper limb, it was hard for her to raise, she took Riluzole without any effect. She wants a better treatment so she comes to our hospital.
Her spirit is good, her sleep is bad, she could only sleep 5 hours under some medicines, her diets are normal, she defecates twice a week, she takes some medicines for urination.

Admission PE:
Bp: 135/82mmHg, Hr: 84/min, breathing rate: 18/mim, body temperature: 36 degrees. Height 159cm, weight 63Kg. Nutrition status is good, normal physical development. There is no injury or bleeding spots of her skin and mucosa, no blausucht. The chest develop is normal, chest movement was basically normal. Breathing sounds of both lungs were clear, no obvious dry or moist rales. The heart beat is powerful with regular cardiac rhythm, with no obvious murmur in the valves. The abdomen was bulge, no mass or tenderness. The liver and spleen were normal, shifting dullness is negative. The spine column is normal, there was slight edema of lower limbs, patient had feet drop.

Nervous System Examination:
Patient was alert and hermental status is good,clear speech. Her memory, the orientation and calculation ability were normal .Both pupils were equal in size and round, diameter as 3.5mm, react well to light, eyeballs can move freely. No nystagmus. Bilateral forehead wrinkle and nasolabial fold are symmetrical, show teeth is normal. Her tongue is in middle and no tongue muscle atrophy, she can move her tongue freely. She can chewing food and blow out the cheek as normal, her tongue can touch the cheek powerfully. Soft plate can lift powerfully. She can close eyes powerfully. Neck was soft, she can turn her neck powerfully. Patient shrug ability is slightly weak, the right arm adductor muscles and proximal muscle power was 5- degree, distal abductor muscle power was 3+ degree, right hand grip force was 5- degree; muscle power of left arm was 5- degree, grip force of left hand was 5 degree, muscle power of right lower limb was 1 degree, of left lower lim was 1+ degree. Muscle tone of upper limbs was normal, of lower limbs slightly lower than normal. Bilateral biceps reflex and radial periosteal reflex are normal, the patellar tendon reflex and tendon reflex can not be induced, bilateral palm-jerk reflex was negative, Hoffmann sign of both sides were negative, Rossilimo sign of both sides were negative; patient can perform the finger to nose test, fast alternate movement and finger opposite movement stable. She can not perform the Heel-knee-tibia test, the meningeal irritation sign is negative.

Treatment:
After the admission, she received related examinations and diagnosed with 1. ALS 2.Diabetes (type 2). She received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair her damaged nerves, replace dead nerves with new injected stem cells, nourish nerves, regulate her immune system and improve blood circulation, with rehabilitation training.     

Post-treatment:
After 14 days’ treatment, her sleep got better, upper limbs muscle power increased, and her endurance improved. Right arm adductor muscles power was 4+ degree; grip force 5 degree. She can stretch her knee joints much flexible once bend her knee passively. Her muscle power of adduction and abduction improved when bending her knee, the muscle power of it is 2+ degree.

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