Mr.Moore-Amyotrophic Lateral Sclerosis-(Russia)-Posted on June 13th, 2017

Name: Mr.Moore
Sex: Male
Nationality: Russian
Age: 50Y
Diagnosis: Amyotrophic Lateral Sclerosis
Date of Admission: December 31th, 2016
Treatment hospital/period: Wu Medical Center/14 days

Before treatment:
Mr.Moore felt down in May 2015. His hindbrain felt down to ground, he was in a coma and taken to hospital. When he woke up, his left hand was weak, it was hard for him to swallow and to speak. The examination result showed his cervical spine was damaged so he was diagnosed with cervical spondylopathy of the spinal cord. In July he had surgery and after that his hand was a little more powerful and he could speak and swallow normally. But he felt his arms had become weak again, there was fascicular twitching, his left shoulder was painful and  the condition became worse. In October 2015, his legs were weak, his balance function was bad, it was hard for him to chew or swallow and he couldn’t speak clearly. He was diagnosed with Amyotrophic Lateral Sclerosis in November 2015 in Israel. He took Riluzole for 6 months without any improvement. His disease became worse, and in March 2016 he could walk only with a walker. He had examinations in Moscow in June and it found that lead level in his blood was much higher than normal. At present he is unable to eat, put on clothes, sit up, stand up or walk. He chokes when eats a liquid diet or drinks water. He is unable to speak clearly and he wants a better life so he came to our hospital.
His spirit is normal. He eats liquid food. He sleeps well. His bladder and bowel actions are normal. He has lost 8 Kgs.

Admission PE:
Bp: 127/80mmHg, Hr: 78/min, breathing rate: 19/mim, body temperature: 36.5 degrees, height: 184cm, weight: 95kg. Nutrition status is normal with normal physical development. There is no injury or bleeding spots of his skin and mucosa, no blausucht. There is a little throat congestion and his tonsils do not have swelling. Chest develop is normal, thoracic mobility abated, the respiratory sounds in both lungs are low, there is no dry or moist rales. The heart beat is powerful, with no obvious murmur in the valves. The abdomen is flat, with no masses or tenderness. His liver and spleen are normal, there is edema in both legs, skin temperature is normal, fluctuations of dorsalis pedis artery are normal.

Nervous System Examination:
Patient is alert and his spirit is good. He has dysarthria. His speech is unclear. His memory, orientation and calculation ability are normal. Both pupils are equal in size and round, diameter is 3mm, react well to light, eyeballs can move freely. No nystagmus. Bilateral forehead wrinkle and nasolabial fold are symmetrical, his tongue is in middle, with mild tongue muscle atrophy and fibrillation. His tongue can reach the lip only. Movement of the tongue muscle is limited and his tongue can not touch the cheek. Showing teeth is normal. Patient can bulge his cheek but with air leakage and his chewing ability is weak. Bilateral supraspinatus, infraspinatus muscles, both arms muscles, bilateral thenar muscles, hypothenar muscles and interosseous muscles in the both hands are atrophied. His neck muscles are soft, his head movement and shrug power are weak. His right arm muscle strength is at level 5-, the left  arm muscle strength is at level 5, both his hands grip strength is at level 4, both legs muscle strength is at level 3 and the four limbs’ muscle tension is high. The tendon reflex of the four limbs is overactive. Bilateral Hoffmann sign of both sides are negative, the Babinski signs are positive. His both hands cannot finish the finger to nose test, the fast alternative test and finger to finger test, because of the low muscle force. Meningeal irritation sign is negative.

Treatment:
After the admission he was diagnosed with Amyotrophic lateral sclerosis. He received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair his damaged motor nerves, replace dead nerves with new injected stem cells, nourish nerves, regulate his immune system and improve blood circulation. This was done along with rehabilitation training.     

Post-treatment:
After 14 days of treatment movement function of all limbs was better than before with increased muscle strength. The muscle strength in the legs increased 1 level. His spirit and energy were better.