Frederick Dane-Amyotrophic Lateral Sclerosis-(Canada)-Posted on Sept.6th, 2017

Name: Frederick Dane
Sex: Male
Nationality: Canadian
Age: 60Y
Diagnosis: Amyotrophic Lateral Sclerosis (ALS)
Date of Admission: Feb. 25th, 2017
Treatment hospital/period: Wu Medical Center/14 days

Before treatment:
The patient tired easily 5 years ago and his condition became worse. His hands and feet were numb 9 months ago and he had muscle pain and stiffness. Eight months ago he went to a local hospital and was diagnosed with Amyotrophic Lateral Sclerosis. He then had swallowing problems 2 months ago. He wants a better life so he came to our hospital.
His spirit and diet are normal. His defecation is normal and he urinates 3 times during the night.

Admission PE:
Bp: 153/89mmHg, Hr: 61/min, breathing rate: 20/min, body temperature: 36.2 degrees. Height 186cm, weight 88Kg. Nutrition status is normal with normal physical development. There is no injury or bleeding spots of his skin and mucosa, no blausucht, no throat congestion, and his tonsils do not have swelling. Chest development is normal, the respiratory sounds in both lungs were clear, breathing sound of the right side is slightly weaker than the left side, there was no dry or moist rales. The heart beat is powerful with regular cardiac rhythm and with no obvious murmur in the valves. The abdomen was soft and bulging, with no masses or tenderness.  The liver and spleen were normal, shifting dullness test is negative. The spinal column is normal and there was no edema in either leg.

Nervous System Examination:
Patient was alert and mental status was good. His speech, orientation and calculation abilities were normal but short term memory ability is not very good. Both pupils were equal in size, round, diameter of 3 mm, react well to light and the eyeballs can move freely. There was no nystagmus. Bilateral forehead wrinkle and nasolabial fold are symmetrical, his tongue is in the middle with no tongue muscle atrophy and showing the teeth is normal. Bilateral soft palate can lift as normal and he can chew as normal. He can close his eyes powerfully. There is mild muscle atrophy of the shoulders and arms, muscle volume of the legs is reduced. Neck is soft and he can shrug as normal. Muscle power of the arms is 5 degrees, grip force of both hands is 5 degrees. Muscle power of the legs is 5 degrees. Muscle tone of all 4 limbs is normal. Ankle clonus is negative. The bilateral biceps reflex, radial periosteal reflex and patellar tendon reflex show hyperactivity. The tendon reflex cannot be induced by examination. The palm-jaw reflex of both sides is negative. Hoffmann sign of both sides are negative, the Babinski sign of both sides are negative. Fast alternate movement is clumsy. The finger to nose test, the fingers opposite movement and heel-knee-tibia test are basically normal. The Meningeal irritation sign is negative.

Treatment:
After the admission, he received related examinations and was diagnosed with ALS. He received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair his damaged nerves, replace dead nerves with new injected stem cells, nourish nerves, regulate his immune system and improve blood circulation. This was done  with rehabilitation training.     

Post-treatment:
After 14 days treatment his exercise tolerance was better. The muscle power of all four limbs was improved, his muscle pain and stiffness were improved and his swallowing function was improved.

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