Toloza Alberto Exequiel-Cerebral Palsy-(Argentina)-Update on Mar.22th, 2018

The second round of treatment:

Name: Toloza Alberto Exequiel
Sex: Male
Nationality: Argentinean
Age: 5Y
Diagnosis: Cerebral Palsy
Date of Admission: Sept. 27th, 2017
Treatment hospital/period: Wu Medical Center/21 days

Before treatment:
The patient’s mother had hypertension when she was pregnant at 32 weeks, and she had an emergency caesarean 3 weeks later due to intrauterine hypoxia. The child's weight was 3.9kg when he was born. On delivery he didn’t cry and didn’t breathe. He had six epileptic seizures in 4 days and  cardiac arrest three times. He went home 1 month later. His breathing and eating were normal but his intelligence and motor functions were delayed. He was brought to our hospital last year and after the treatment his eyes chased light and he spoke more words. The muscle tension of the four limbs was lower and he grasped with his hands. For now, his intelligence function is behind other children at the same age, he speaks some words, his vision function is not so good, the power of his neck is bad, sometimes he raises his head in a prone position, the muscle power of his trunk is bad and he is unable to sit up, stand or walk.
He takes medicines to sleep, eats a liquid diet, his urination function is normal but he needs help with defecation.

Admission PE:
Bp: 112/64mmHg, Hr: 107/min, breathing rate: 24/min, body temperature: 36 degrees. Height: 92cm, weight: 12kg. Nutrition status is poor, physical development is delayed. There is no injury or bleeding spots of his skin and mucosa and no blausucht. The mouth color was mildly pale, no obvious pharyngeal hyperemia and the tonsils had mild swelling. There was obvious throat singing sounds, the bilateral chest development was symmetrical, breathing sound was clear with no rales. The heart beat is powerful with regular cardiac rhythm and with no obvious murmur in the valves. The abdomen was flat and soft with no masses or tenderness. The liver and spleen were normal by touch.

Nervous System Examination:
Patient was alert but he could not speak having only few a sounds such as “awa, a”. He could not complete the examination of memory, orientation and calculation ability. Both pupils were equal in size and round with a diameter of 3 mm, react well to light, his eyes could not chase objects. The eye movement was discordant and sometimes he had a fixed  gaze upward. He could not complete the cranial nerve examination, chewing ability was very poor, he could take semi-liquid food but the swallowing function was normal with no choking. He could not complete the muscle power examination, his neck was soft and weak, he could turn his head in a prone position and raise his head up. The trunk muscle was weak, he could not roll over in bed himself, sit up, stand or walk. His 4 limbs movement ability was very limited. His hands had some grasping action but there was no voluntary movement of the legs. Muscle tone of all 4 limbs was increased. Tendon reflex of the 4 limbs was active, abdomen reflex was normal, sucking reflex of both sides was negative, Babinski sign was positive. He could not complete the sensory and coordinator movement examination. The meningeal irritation sign is negative.

After the admission he received related examinations and received 4 neural stem cell injections and 4 mesenchymal stem cell injections to repair his damaged nerves, replace dead nerves with new injected stem cells, nourish nerves, regulate his immune system and improve blood circulation. This was done with rehabilitation training.     

After 21 days treatment he spoke more words, his swallowing function was better, he ate faster, the muscle power of his neck and head was increased and he was able to raise his head for longer. His muscle tone decreased, the trunk spasm alleviated and he was able to maintain a sitting position with someone’s help. His hands were more flexible, he was able to raise his arms and grasp things. He had more power in his legs and he was now able to stand with someone’s help.

The first round of treatment:

Date of Admission: August 16th, 2016
Treatment hospital/period: Wu Medical Center/21days

Before treatment:
When Toloza’s mother was pregnant for 32 weeks, she had hypertension and when she pregnant for 35 weeks, she had intrauterine oxygen deficit, so she received cesarean section. When Toloza was born, his weight was 3.9kg, he didn’t cry or breathe, he had 6 times epileptic attack in 4 days and 3 times  cardiac arrest, he had emergency treatment and out of dangers. He stayed in hospital for 1 month and went home. His breath and diet were normal when he back home, but his intelligence and motor development were delayed, he was diagnosed with cerebral palsy. He had no epileptic attack after he went home. His intelligence was worse than other kids, he was unable to speak, sometimes, he spoke a few non-meaning words. His vision function was bad, when he see strong light in darkness he would blink his eyes, but his eyes didn’t chase light or moving objects, he had hearing function. He controlled his neck bad, he could raise head for a movement in prone posture, his trunk had less power, he was unable to turn over, sit up, keeping in sitting position, stand or walk. His for limbs were able to move, he had no automatic action. His parents wanted him to have a better life, so they took him to our hospital.
His nutritional status was good, he needed medicines to sleep. He had liquid diet. He needed help for defecation, his urination was normal.

Admission PE:
Bp: 90/50mmHg. Hr: 114/min. Br: 34/min. Body temperature: 37.2 degree. His physical development and nutritional status were bad, his Height: 84 cms, weight: 11kgs. The skin and mucosa were normal, without yellow stains or petechia. His lips were mild pale, he had swelling and congestion of throat. His tonsils were enlarged, there were phlegm noise and throat noise in parslaryngea pharyngs, the noise will be obvious when he was nervous. His bony thorax was symmetrical. The respiratory sounds in both lungs were rough, with no dry or moist rales. His heart sound was strong, the cardiac rate was normal, there was no obvious murmur in the valves. His abdomen was flat and soft, there was no pressing pain or rebound tenderness. We didn’t touch his liver or spleen under the ribs.

Nervous System Examination:
Toloza Alberto Exequiel was alert, he was unable to speak. He was unable to finish the memory, orientation ability or calculation examinations. Both pupils were equal in size and round, the diameter was 3.0mms, both pupils were sensitive to light stimulus. His eyes were unable to chase moving objects and his eyeballs’ movements were incoordinate. His eyeballs always looked upward. He didn’t cooperate with cranial nerves’ examinations. He was unable to chew, so he ate fluid food, his swallowing function was normal, sometimes he chocked when he swallowing. His trunk and neck always had torsion spasm. His neck was powerless, he didn’t cooperate with muscle power examinations. He was able to turn over his head and raise head for a while in ventral position. His trunk was powerless, he was unable to turn over his body, sit up, keep in sitting position, stand or walk. The movements of four limbs were bad. When he made a fist, it was hard for him to open it. He was unable to raise arms or grasp objects by himself. His lower limbs had no active movement. The muscle tension of four limbs’ was higher. The tendon reflex of four limbs was active, abdominal reflexes were normal. Babinski sign was positive. His meningeal irritation sign was negative.

Toloza Alberto Exequiel was diagnosed with cerebral palsy, he received 4 neural stem cell injections and 4 mesenchymal stem cell injections to repair his damaged nerves, replace dead nerves with new injected stem cells, active stem cells in his body, regulate his immune system, improve his blood circulations, nourish neurons and improve nutritional status. He also had physical rehabilitation.         

After 21days of treatment, his weight was 12 Kgs, his vision was better, his eyeballs were able to chase light. His language function was improved, he could speak more words, such as “ah”, ”oh”, ”wu” and other single words. The muscle tension of four limbs was lower, his trunk had less twist and spasm. His neck and head’s twist were better. His lower limbs’ scissors status was less. His upper limbs’ movements were more, he showed some grasping movements.




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