Fujio Sato - Parkinson's disease (Japan) Posted on January 7,2012

Name: Fujio Sato                  
Sex: Male
Country: Japan
Age: 59
Diagnoses: 1.Parkinson's disease 2. Plasma hyperhomocysteinemia
Admission Date: November 27, 2012
Days Admitted to Hospital: 26 days

Before treatment:
Fujio Sato suffered from tremor of the right hand and went to a local hospital. He took clonazepam and his condition improved. The tremor was aggravated in 2003 and then began suffering from tremors in both hands. His lower limbs were slowly presented with bradykinesia. He was diagnosed with Parkinson's disease and the disease became aggravated gradually over time. The patient was presented with static tremor - lack of expression. The times of scardamyxis was reduced. The walking posture changed to a flexion position. He walked with small steps - bradykinesia. The writing was typical lowercase. He took many medications for treatment, such as Levodopa/carbidopa, Pramipexole, selegiline and so on. Part of the symptoms could be controlled, but the disease still became aggravated gradually over time. He walked with an obvious switch phenomenon.

Nervous System Examination:

Fujio Sato was alert. His speech was unclear. His talking speed was almost normal. The memory, calculation ability and orientation were normal. Both pupils were equal in size and round, the diameter was about 3.0mms. The movements of both eyeballs were flexible and both pupils were sensitive to light stimuli. There was facial masking. The times of scardamyxis was reduced. The forehead wrinkle pattern was symmetrical. The nasolabial groove was symmetrical. The tongue was centered in the oral cavity and the teeth were shown without deflection. There were tremors in the genioglossus. The raising ability of the soft palate was almost normal. He could turn head flexibly. The shrug muscle strength of shoulders was weak. The muscle strength of the upper limbs was level 5, the muscle strength of both lower limbs was level 4. Bilateral Wax-Waning Sign was positive. The muscle tone of both upper limbs was increased. The muscle tone of both lower limbs was normal. The tendon reflex of both upper limbs existed. The tendon reflex of both lower limbs was reduced. Bilateral abdominal reflexes were normal. The bilateral Hoffmann's sign was negative. Bilateral sucking reflex was negative. The bilateral palm jaw reflex was negative. The bilateral Babinski's sign was negative. The deep, shallow, and epicritic sensation was normal. Both upper limbs had static tremor. Both sides of the body were able to finish the finger-to-nose test, digit opposition test and rapid rotation test, but in a clumsy manner. Handwriting had micrographia sign. Both sides of the body did the heel-knee-shin test in an unstable manner. The posture was presented with flexion when he walked. The starting walk was slow, march a petit pas and had difficulty with turning round. The Romberg's sign was positive. There were no signs of meningeal irritation. The laboratory test: HCY was increased.

Treatment:
Fujio Sato received treatment starting on November 27, 2012. He received treatment to expand blood vessels to increase the blood-supply, neural regeneration, neural repair and he was given nerve nutrition. He also received treatment to get rid of the oxygen free radicals in the brain. This was combined with physical rehabilitation training.

Post-treatment:
The patient has better facial expression. The tremor of lingualis has disappeared. His speech is clearer than before. The static tremor has almost disappeared. Occasionally, he has tremor in the end of the finger when he is nervous. The switch sign has almost disappeared. The handwriting micrographia sign has disappeared. The muscle strength of both lower limbs has increased and reached level 5. The balance ability is better than before. There is no difficulty when starting to walk and the walking gait is normal. The walking speed is obviously better than before and the endurance in exercises has increased. He can turn around more flexibly and the speed has increased. Both sides of the body are able to finish the finger-to-nose test, digit opposition test and rapid rotation test in a more stable manner. The Romberg's sign has disappeared. He can stand on a single leg, but the standing time is still slightly shorter than normal. The laboratory test: HCY is normal.