Huu Long Nguyen-Parkinson's disease(Vietnam)

The third round of treatment:

Name: Huu Long Nguyen
Sex:
Male
Nationality:
Vietnamese
Age:
55Y
Diagnoses:
Parkinson's disease
Discharge Date:
2018/02/20

Before treatment:
The patient felt stiffness in his limbs without any reason 10 years ago. He moved slowly, his right hand shook when he wrote, he wrote letters smaller and  smaller when he continually wrote. His condition became worse and worse, his life and work were affected. He went to a hospital 1 year later and was diagnosed with Parkinson's disease. He took medicines and his condition became better but his disease progressed slowly. His medicines were adjusted 6 years ago, he began to take Sinemet but the side effect was bad. He had amaurosis, so he took less doses of it and his work and life were affected obviously. He went to our hospital 3 times and after treatment his condition became better, he could work and had a normal life.
His diet and sleep are good, his urination and defecation functions are good. He put on 5 kgs six years ago after our treatment.

Admission PE:
Bp: 136/89mmHg; Hr: 75/min. RP:19/min. His body shape was good and his gait was normal without arms swinging. It was easy for him to get tired and his nutrition was normal. There was no ecchymosis, petechia or yellow stains on his skin. There was no congestion in the pharyngeal area and the tonsils were not enlarged. The respiration in both lungs was clear with no dry or moist rales. Through auscultation the heart sound was strong with no murmur in each valve. The abdomen was flat and soft, his abdominal muscle was a little tense but without tenderness or rebound tenderness. There were no masses. The liver and spleen were not touched under the rib. There was no swelling in either leg.

Nervous System Examination:
Huu Long Nguyen was alert and his speech was a little slurred but his speech speed was passable. His memory, orientation and calculation abilities were normal. His facial expression was not as rich as normal. Both pupils were equal in size and round, the diameter was about 3.0mm. Both pupils were sensitive to light stimulus and both eyeballs could move freely to each side. He had no nystagmus. The forehead wrinkle pattern was symmetrical and bilateral nasolabial grooves was symmetrical. The tongue was in the center of oral cavity and there was no tremor, he had strong muscle power to lift his soft palate and the uvula had not deflected. He could turn his head freely though it looked rigid when turning left. The movement of the four limbs was a little slow but without obvious tremor. The muscle power of the left side was at level 5-, right side was at level 4+. Sometimes he turned over, stood up and walked slowly. He had no obvious starting difficulty to walk, his walking speed was passable but he was a little unstable to turn around. The muscle tension of the four limbs was normal. Bilateral biceps, triceps brachii and radial periosteal reflex were normal. Both sides patella tendon reflex and achilles reflex were lower. Bilateral Hoffmann sign, Rossilomo sign, bilateral sucking reflex, bilateral palm jaw reflex and bilateral Babinski sign were negative. Bilateral deep, shallow and fine sensation was normal. Right side finger to finger movement and rapid alternating movement was a little clumsy, while he did it flexibly on the left side. Bilateral finger to nose movement was flexible. He did the heel-knee-tibia test in a stable manner. The Romberg sign was weakly positive. He always bent forward when walking. Meningeal irritation sign was negative.

Treatment:
The patient received 2 times nerve regeneration treatment(neural stem cells and mesenchymal stem cells) to repair damaged nerves, replace dead nerves, active stem cells in his body, Anti-Parkinson, to provide nourishment to the neurons, expand the blood vessels in order to improve the blood supply to the brain and stabilize organ function. This was combined with physical rehabilitation training.          

Post-treatment:
After 7 days of treatment he was in a stable condition, his spirit was good and he could move freely. He spoke more clearly, his expression was higher, his neck became free to move, his limbs were flexible and he moved faster. He could take good care of himself.

The second round of treatment:
Diagnoses: Parkinson's disease
Date of Admission: Sept. 25th, 2016

Before treatment:
Huu Long Nguyen felt stiffness in limbs without any reason, he moved slowly, his right hand shook when he wrote, he wrote letters more and more smaller when he continually wrote. His condition became worse and worse, his life and work were affected. He went to hospital 1 year later and diagnosed with Parkinson's disease, he took medicines, his condition became better but his disease progressed slowly. His medicines were adjust 4years ago, he began to take Sinemet, but the side effect was bad, he had amaurosis, so he took less dose of it, his work and life were affected obviously. He went to our hospital in May 2013 and February 2015 to do stem cells treatment, and after treatment, his condition became better, he could work and had a normal. At present, his limbs are slowly to move, he speaks slowly, his right shoulder, neck and right upper limb are stiffness. He wants a better life so he comes to our hospital again.
His diet and sleep are good, his urination and defecation are good. He put up 5 kgs 4 years ago after our treatment.

Admission PE:
Bp: 120/80mmHg; Hr: 69/min. RP:18/min. His body shape was good, his movement of swing arms were not very flexible. He was easy to get tired and his nutrition was normal. There was no ecchymosis, petechia or yellow stains on skin. There was no congestion in pharyngeal area. The tonsil was not enlarged. The respiration in both lungs was clear, no dry or moist rales. Through auscultation, the heart sound was strong, with no murmur in each valve. The abdomen was flat and soft, his abdominal muscle was a little tension without tenderness or rebound tenderness. There was no mass. The liver and spleen was not touched under the rib. There was no swelling in both lower limbs.

Nervous System Examination:
Huu Long Nguyen was alert and his speech was not clear but fast. His memory, orientation and calculation were normal. His facial expression was not much. Both pupils were equal in size and round, the diameter was about 3.0mm. Both pupil was sensitive to light stimulus. Both eyeballs could move freely to each side. He had no nystagmus. The forehead wrinkle pattern was symmetrical and bilateral nasolabial grooves was symmetrical. The tongue was in the center of oral cavity. There was no tremor in tongue. He had strong muscle to lift his soft palate. The uvula had not deflected. He could turn head effective,. The movement four limbs were a little slowly without tremor. The muscle power of left side was at level 5, right side was at level 5-. Sometimes he turned over, got up and walked slowly. He had no obvious difficult to start to walk, the speed was good. The muscle tension of four limbs was normal. Bilateral biceps, triceps brachii and radial periosteal reflex were normal. Both side patella tendon reflex and achilles reflex were lower. Bilateral Hoffmann sign, Rossilomo sign, bilateral sucking reflex, bilateral palm jaw reflex, bilateral Babinski sign were negative. The depth sensation and epicritic sensibility were normal. He couldn’t do alternate motion and finger-to-finger test in right side very well, but the left side was normal. Both side finger-to-nose texts were good. He did the heel-knee-tibia test in a stable manner. The Romberg sign was weakly positive. He always bent forward when he walking. Meningeal irritation sign was negative.

Treatment:
Huu Long Nguyen was diagnosed with Parkinson’s disease. He received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair damaged nerves, replace dead nerves with new injected stem cells, active stem cells in his body, Anti-Parkinson, to provide nourishment to the neurons, expand the blood vessels in order to improve the blood supply to the brain and stabilize organ function. This was combined with physical rehabilitation training.          

Post-treatment:
After 10 days of treatment, his was in stable condition, his spirit and mood was good, he could speak fluently, he could move freely. He could take good care of himself. His right shoulder, neck and upper limb were more flexible.

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